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KMID : 0829220150390020413
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Korean Journal of Oral and Maxillofacial Pathology
2015 Volume.39 No. 2 p.413 ~ p.420
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The Morphologic and Architectural Characteristics of Adenocarcinoma, NOS in the Salivary Glands
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김보경:Kim Bo-Kyoung
강경림:Kang Kyung-Rim/이재일:Lee Jae-Il
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Abstract
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As the designated name, adenocarcinoma, not otherwise specific (ANOS) revealed lack of histomorphologic characteristics that could classify the tumors under specific name. ANOS had nothing in common with other salivary gland malignancies, but glandular differentiation. The purpose of this study is to find out the solid characteristics of ANOS on the base of cytological and architectural features. 20 ANOS cases were studied. We identified 20 patients with salivary adenocarcinoma, not otherwise specified, ranging in age from 26 to 76 years (median, 53.85 years), with slight female predilection (female 11: male 9). The minor salivary gland was the most common site of tumor origin, especially on the palatal area (11 out of 20). The size of tumor was from 1.0 to 7.0(median 3.07). For the histopathological analysis, we classified the tumors by cytological and architecture patterns. Basaloid and epitheloid cytological patterns were showed with solid, microcystic/pseudocystic architecture. We found invasive growth patterns in 7 out of 20 cases. Reviewing and classifying the common features of ANOS could be helpful to make a diagnosis of malignant salivary gland tumors.
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KEYWORD
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ANOS, Adenocarcinoma, Not Otherwise Specified, Myoepithelial Cells, Salivary Gland Tumor
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